7 Best Chemical Compliance Software of 2024

chemical safety officers checking compliance measures in accordance with the guidelines outlined in chemical compliance software

Why use SafetyCulture?

SafetyCulture is a user-friendly platform that monitors and ensures chemical compliance by using digital safety sheets, properly labeling chemical compounds, and establishing safe and compliant workflows for employees. The platform features checklists for adherence to important standards for the chemical industry, such as ISO 9001, while allowing companies to train employees in compliant practices. It’s easily customizable and will enable you to collect data in real-time while conveniently reporting, tracking, and analyzing trends.


  • Maintain compliance with relevant chemical regulations with comprehensive process inspection and audit checklists.
  • Collect data on chemical compliance and spot non-compliance trends, making it easier to create compliant workflows and improved strategies.
  • Ensure that managers stay on top of operations by allowing workers to report non-compliance issues so that they can assign corrective actions.
  • Constantly monitor the conditions of storage facilities to ensure they remain compliant with relevant standards using sensors and monitoring devices.
  • Train a skilled workforce that understands the importance of compliance and how to maintain it throughout operations.

Why use ETQ Reliance?

ETQ Reliance is a Quality Management Software (QMS) that assists organizations in maintaining chemical compliance. Through this easy-to-use platform, organizations can analyze data and ensure quality while saving time and effort by automating chemical manufacturing processes.


  • Environment, Health, and Safety (EHS) reports
  • Customizable alerts
  • Business analytics

Why use Sphera?

The Sphera platform allows companies to consolidate their chemical compliance data in one place, making improving safety and minimizing risks easier. The data collection also allows companies to keep a clear record of their compliance, making it easier to stay transparent.


  • Easy-to-access safety data
  • Automated reporting
  • Right-to-Know compliance

Why use VelocityEHS?

VelocityEHS allows companies to keep tabs on chemical inventory, create ingredient indices, and generate reports, making it much easier for companies to maintain chemical compliance. The platform allows you to take compliance practices to the digital world, lowering costs and boosting efficiency.


  • Cross-facility inventory tracking
  • Safety Data Sheet (SDS) management
  • Regulatory reporting

Why use Chemwatch?

Chemwatch is specifically designed for chemical management, making it a great option for companies looking to improve their chemical compliance. The platform helps companies of all sizes manage chemical risks and adhere to global regulations, making compliance much easier.


  • Risk assessments
  • Reporting
  • Chemical registers and manifest

Why use 3E?

3E is a powerful chemical compliance platform, offering SDS monitoring and other digital solutions to enhance an organization’s compliance. The platform also has features for emergency response and hazardous waste management, making it a useful tool for modern organizations.


  • SDS indexation
  • Chemical classification
  • Product and material ingredient screening

Why use Quentic?

Quentic offers various features that allow organizations to manage and monitor compliance digitally. This makes it much easier for managers to spot areas of non-compliance and implement solutions to ensure that everyone complies with relevant regulations.


  • Environmental management
  • Incidents and observations
  • Chemical registers

What is Chemical Compliance Software?

Chemical compliance software is a specialized tool designed to help organizations manage and streamline their chemical safety, regulatory compliance, and hazard communication processes. This software ensures adherence to all relevant safety and environmental guidelines imposed by regulatory bodies, minimizes risk, and optimizes overall chemical management.


Implementing robust chemical compliance software is crucial for businesses. This software provides a comprehensive solution for managing chemical inventory and compliance requirements effectively, ensuring that businesses can confidently navigate the complex landscape of regulations and safety protocols.

Ensure Compliance

The software offers a systematic approach to compliance, helping businesses stay up-to-date with evolving regulations and standards. By centralizing compliance efforts, it ensures that businesses can easily demonstrate adherence to regulatory requirements, avoiding penalties and fines.

Streamlined Risk Management

Businesses benefit from streamlined risk management processes, as the software facilitates the identification, assessment, and mitigation of potential hazards associated with chemical use. This proactive approach minimizes the likelihood of accidents or incidents, enhancing overall workplace safety.

Reduced Liability

With the software’s comprehensive features for managing chemical inventory and compliance, businesses can significantly reduce their liability exposure. By implementing best practices and ensuring regulatory compliance, businesses mitigate the risk of legal disputes and financial repercussions associated with non-compliance.

Key Features

Chemical compliance software should come with features that fit your organization’s needs, which is why every company needs different software. That said, there are some key features that are crucial when selecting chemical compliance software, such as the following:

How to Choose the Right Chemical Compliance Software

Choosing the best compliance software for the company’s needs can be quite a task. So, here’s a comparison of the options mentioned above to make it easier for you to choose the best fit for your organization.

Chemical Compliance Software Free Version Paid Plan Mobile App
SafetyCulture Yes $24/user/month* Yes
ETQ Reliance No Contact vendor for pricing Yes
Sphera No Contact vendor for pricing Yes
VelocityEHS No Contact vendor for pricing Yes
Chemwatch No Contact vendor for pricing Yes
3E No Contact vendor for pricing Yes
Quentic No Contact vendor for pricing Yes

* billed annually

Leon Altomonte
Article by

Leon Altomonte

SafetyCulture Content Contributor
Leon Altomonte is a content contributor for SafetyCulture. With his language degree and years of experience in content writing, he delivers well-researched, informative articles about safety, quality, and operational excellence. In addition to his professional pursuits, Leon maintains a creative outlet as a performing musician.